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Huntington’s disease – Symptoms, causes, and management

Huntington’s disease – Symptoms, causes, and management
In the realm of neurological disorders, Huntington’s Disease (HD) stands as a formidable adversary, relentlessly encroaching upon the lives of those afflicted. HD is a hereditary, progressive neurodegenerative disorder that impairs both motor and cognitive functions, leading to a profound deterioration in an individual’s quality of life. With a genetic underpinning involving the expansion of CAG trinucleotide repeats, HD presents a complex clinical picture characterized by a range of motor symptoms, cognitive impairments, and psychiatric manifestations. Motor symptoms Chorea One of the hallmark symptoms of Huntington’s Disease is chorea, characterized by involuntary, jerky, and unpredictable movements of the limbs, face, and other body parts. These movements can be mild or severe and often interfere with activities of daily living. Dystonia Individuals with HD may experience muscle contractions and abnormal postures known as dystonia. This symptom can lead to sustained muscle contractions, causing discomfort and difficulty maintaining a normal posture. Bradykinesia As the disease progresses, individuals may develop bradykinesia, a slowness of voluntary movements. This can affect one’s ability to initiate and complete tasks. Impaired coordination Huntington’s disease often leads to impaired coordination and balance. Individuals may have difficulty walking and may become prone to falls. Difficulty swallowing Dysphagia, or difficulty swallowing, is a common symptom in advanced stages of HD.

8 first-line treatments for atopic dermatitis in infants

8 first-line treatments for atopic dermatitis in infants
In dermatology, atopic dermatitis is a unique and uncommon condition emerging due to exposure to ionizing radiation. This specialized skin disorder presents a distinct set of challenges for those who experience it. This article explores atopic dermatitis from a third-person perspective, delving into its origins, symptoms, and treatment modalities. This article also sheds light on the intricacies of a condition that arises from the intersection of dermatology and radiation exposure. Some facts about atopic dermatitis in children Atopic dermatitis is a life-long (chronic) skin disorder common in infants and children. A child with a history of allergies or family members having atopic dermatitis has a higher chance of having atopic dermatitis. Itching, dryness, and redness are common symptoms. The treatment goals are to ease inflammation and itching of the skin, increase moisture, and prevent infection. Staying away from triggers is essential to manage the condition. The condition gradually improves or begins to disappear as a child gets older. Topical creams are usually the first line of treatment for children. Treatment options The management of atopic dermatitis is multifaceted, aiming to relieve symptoms, promote healing, and prevent complications. Treatment plans are tailored to the individual’s condition and may include the following approaches.

7 cruises to avoid

7 cruises to avoid
A cruise vacation can be exciting, with all kinds of onboard events to look forward to and a charming itinerary filled with nightlight, buffets, and the open seas. However, not every cruise package is created equal, and some trips on the sea can be underwhelming. So, it is important to do a little research before booking a cruise and choose top-rated options. Further, here are a few cruises to avoid for a hassle-free vacation: 1. Short cruises during spring break A cruise trip during spring break can seem ideal because of the perfect weather in places like the Caribbean. Even the ports are not too crowded, and one can take kids along during their school break. However, even college students get a break during this time and tend to book cruise trips. So, the cruise ship can get overwhelming and chaotic because of the noise and non-stop partying. Instead, one should book a cruise to the Caribbean during January if they want a more relaxing experience at the sea. If one must book one during spring break, they should look for less party-centric cruise lines. 2. First and last Alaska cruises of the season Destinations like Alaska are perfect spots for tourists because of the rainy weather and luscious green mountains they can experience.

8 early signs of seizures

8 early signs of seizures
Seizures occur when changes in the brain’s electrical activity cause sudden changes in movement, sensation, awareness, thought, or behavior. Depending on the part of the brain involved, they are categorized into three main types – focal onset seizures, generalized onset seizures, and unknown onset seizures. Although seizures may present themselves differently and with varying intensities, recognizing their early signs is crucial for timely support and intervention. Some of the most commonly reported signs of a seizure include: Aura People who experience seizures often describe feeling an aura beforehand. This sensation can include a variety of feelings, such as visual, auditory, or olfactory sensations, pain, numbness, or headaches. Some examples of aura symptoms include a wave-like sensation that travels through the head, twitching or stiffening of the arm or hand, a feeling of falling or riding a roller coaster in the stomach, an unusual taste or smell, hearing unexplained sounds or music, experiencing sudden, intense emotions like fear, happiness, or anxiety, tingling or numbness, hallucinations, or seeing colored or flashing lights. According to research, around 65 percent of people with generalized epilepsy experience seizures. Auras can be a warning sign of an oncoming seizure, signaling that it may be time to seek assistance and move to a safer place.

5 stages of Huntington’s disease

5 stages of Huntington’s disease
Huntington’s disease is a rare and inherited health disorder that causes the brain’s nerve cells to progressively break down over time. As the cells degenerate, a person’s functional abilities start to decline. Additionally, their movements, cognitive ability, and mental health are also affected. It is similar to having ALS, Parkinson’s, and Alzheimer’s disease simultaneously. These symptoms develop gradually over the course of several years as the disease progresses through multiple stages. Causes of Huntington’s disease Huntington’s disease is a genetic health disorder. It results from a difference or mutation in a particular gene. This difference is generally inherited. Thus, Huntington’s disease runs in the family. Also, it is an autosomal dominant disorder. This implies that only one copy of the different gene is enough for a person to develop this disorder. Thus, a child has a 50% chance of inheriting the nontypical gene from a parent, who may pass along a healthy or nontypical copy of the gene. Therefore, if both parents have Huntington’s disease, there is a 100% chance that their child may have it, too. Progression of Huntington’s disease The atypical gene that causes Huntington’s disease is present in a person at birth. However, the symptoms do not start manifesting at that time.

14 early signs of severe respiratory viral infections

14 early signs of severe respiratory viral infections
In recent years, respiratory illnesses have been on the rise, especially those caused by viruses. Such diseases can affect the entire respiratory system, from the sinuses to the lungs. Although some symptoms associated with these conditions tend to resolve on their own, others may require medical intervention. That is why recognizing the symptoms early on and getting timely treatment may help in managing the condition. So, here are 14 early signs of respiratory infections: 1. Fever A fever is generally one of the first signs of a respiratory infection. It is the result of the immune response to viruses, as many such pathogens are sensitive to temperature changes in the body. Upon noticing this sign, one must consistently monitor their body temperature, as a persistent fever may be an indication of a severe respiratory virus. Here, seeking medical attention is important if the body temperature crosses 100.4°F (38°C). A temperature as high as 101 to 102°F (about 38.3 to 38.9°C) is common for those infected by influenza. However, fevers over 103°F require immediate treatment. At times, this symptom may be accompanied by night or cold sweats. As the internal temperature increases, the body may induce sweating to prevent overheating and help one cool down.

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6 mistakes to avoid while booking a hotel

Various online platforms have made booking accommodations a breeze. Whether you are traveling within the country or abroad, you need to make sure that you have chosen the right place to say and made the bookings correctly, so there’s no issue when checking in. However, certain common mistakes people tend to make when booking hotels can put a hitch in their trip. Here’s a list of six such booking mistakes that you should avoid: Not clarifying the different elements of the rate Many a time when making a booking, people just see the room rate. They forget to check out other additional components of the room rate. For example, many forget to find out about taxes. If you are booking online, there are resort fees that you may not see immediately and forget to check about. The resort fee is an amount charged for certain amenities at the property and is mostly not part of the basic room rate. You may realize the extra amount to be paid only when you arrive at the hotel, and at that time, it is too late to cancel your booking without paying a hefty fee. Therefore, it is best to gather all information before you make the booking. This way you will not end up being in a sorry state spending more than budgeted for the trip. Choosing non-refundable rates to book the room This could be another big blunder. Non-refundable rates usually are lower rates than the normal rates, that’s why these are so attractive. Sometimes, the non-refundable tag are prominently displayed but at times it can be mentioned in tiny fonts somewhere below that is easy to miss. Unfortunately, situations can change anytime and what was once a confirmed trip, you may need to cancel the booking eventually. There could be an emergency at the home, or office, or you may need to change the dates, etc.

7 things to avoid doing when staying in a hotel

Staying in a luxurious hotel can be exciting. You can enjoy several amenities, personalized services, and complimentary benefits. But you should be cautious. Experts and travel enthusiasts have devised several dos and don’ts to follow when in a hotel to avoid confusion and make the trip more memorable. Special focus should be on the don’ts as these can risk your safety in a new place. Here are seven things to avoid doing in hotels: Opening the door instantly Many instantly reach out for the doorknob on hearing the doorbell or a knock. This is a big mistake. While it is okay to assume that the person on the other side would be a housekeeping staff or an F&B person, it is best never to take a chance. This is especially applicable if you are in another country, traveling for the first time to a place, or staying at the location as a first-time guest. Verify the visitor’s identity before opening the door. You can do so by looking through the peephole or glancing outside through an adjacent window. Letting strangers inside can be costly if they turn out to be someone with the wrong intent. Packing the hotel’s bathrobes in your suitcase This is nothing short of stealing; you could be in big trouble if caught. Besides the legal hassles, pilfering the hotel’s properties speaks poorly about your manners. Taking a small bottle of shampoo, conditioner, or body lotion may be okay because these usually end up in the trash. But not bathrobes for sure. Similarly, do not just pick other linen pieces, small electronic items, or any artwork from the room. Hotels conduct a thorough inspection after you leave and could impose legal charges if the offense is serious. Using throw pillows In luxury hotels, you may see throw pillows lying on sofas, chairs, and other sitting areas.

7 easy ways to accessorize any outfit

Accessories tend to not only enhance your attire but also make you appear vibrant. Be it a casual chic look or an utter formal attire, adding some flash and bling just infuses life into your overall appearance. However, your accessories can perform their assigned role correctly only if perfectly styled. Here are some easy techniques and tips you can apply to up your fashion game and bring the best out of your outfit: Do not pile up on accessories at a time Most people commit the mistake of donning all the available accessories at once with an outfit. It must be noted that as far as accessories are concerned, less is always more. The purpose of using accessories is to highlight your outfit. However, if you adorn your outfit with several accessories like a watch, scarf, jewelry, sunglasses, hat, etc., all at once, none of them will stand out, making your outfit look cluttered and even awful. Highlight neutral clothes with bold accessories While neutral-colored clothes can look dull and understated, they are also the most perfect ones to be used as a field for experiments. If your wardrobe is filled with neutral colors like olive, navy, beige, white, or black, now is the time to boost them by pairing them up with some bold-colored accessories. Here are a few methods to do that: Pair a navy or black dress with a thin hot pink or red belt. Highlight your dull olive or khaki clothes using a flashy yellow or orange scarf. Add some hue to your colorless white blouse by pairing it with big drop earrings or a multicolored statement necklace. Don’t be too matchy While it could be tempting to pair up the blue polka dots of your dress with some matching blue shoes, a blue necklace, and blue earrings, it would make the outfit too predictable, boring, and even childish.

8 must-have accessories for men

Accessories tend to constitute a crucial part of outfits. They are those magical wands that have the power to infuse life into the dullest of clothes. However, they can be equally intimidating if one is unaware of the basic rules of accessorizing and invests in the wrong pieces. So, here is a list of men’s accessories that never go out of style and, therefore, are a must-have in one’s wardrobe. Sunglasses When it comes to accessories, nothing comes close to a pair of sunglasses. They are practical, flattering, and the perfect solution for hiding the shadows under your eyes. Not to forget, they play a vital role in protecting your eyes from the sun’s harmful UV rays. Besides that, they are here to stay for a long time unless broken due to a mishap. Make sure you keep the style classic and subtle with tortoiseshell or black frames and dark green, black, or brown lenses. Wallets While paying for your necessities is now as simple as swiping a card or transferring through a smartphone, the charm of billfold wallets doesn’t seem to subside. And why not? They are practical, strong, yet flexible enough to accommodate their contents effortlessly, and, most importantly, they are durable too. They come in various prints, colors, and designs to suit every personality. One can also get them customized with initials or personal charms. Stainless steel watches These are the practical, no-nonsense cousins of the gold watches with a long lifespan. Besides that, they are extremely versatile. A classy watch can instantly amp up any outfit – be it a formal suit or a casual T-shirt and jeans. One can never go wrong with this men’s accessory. Durable belts Belts are not merely for holding your trousers in place; they also add to your overall look.

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5 styling ideas for women over 60

5 styling ideas for women over 60

Age is a number when setting a true style statement. Regardless of anyone’s perception, just because you are reaching the 60s doesn’t imply to stop working on your appearance and renounce your desires to look fabulous. Fashion is not just merely about trends; it is about how you express yourself through clothes as the myths of age must not limit your expression. So, here are a few best styling ideas for women over 60: Embrace your age One of the most typical fashion mistakes people make is choosing outfits that are supposed to make them appear younger than their actual age. The problem with such a choice is that you are paradoxically accentuating your age when you try to look younger by wearing an outfit that will be more appropriate for youngsters. For example, if you don high heels, short skirts, or flashy fashions that might be more appropriate for a person half your age, you are indirectly making yourself appear “older.” Instead, you can opt for clothes that are specially tailored for women your age. Sporting “age-appropriate” dresses will conceal your age and make others appreciate your other features like glowing skin or your build. And consequently, you will appear much younger than your actual age.
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5 tips to prevent and manage ulcerative colitis

5 tips to prevent and manage ulcerative colitis

Ulcerative colitis is a long-term inflammatory disease that triggers inflammation and ulcers in the digestive system. It impacts the colon and rectum’s innermost lining. The symptoms are typically produced over a period rather than unexpectedly. According to the latest studies, about 1 million people have ulcerative colitis, and if left untreated, it can be crippling and cause life-threatening conditions. So, here are 5 tips to prevent and manage ulcerative colitis: Get on with the treatment plan immediately Even though there is no concrete cure for ulcerative colitis, proper treatment can help ease the symptoms and signs of the condition and eventually provide long-term remission. If a patient feels that their bowel habits are consistently changing or if they experience any of the following symptoms and signs, they should immediately consult a doctor: Blood in stool Ongoing diarrhea that is not getting cured by any other types of treatments An unknown fever going on for more than a day or two Abdominal pain Diarrhea that wakes up the patient from sleep The treatments prescribed by the doctor will typically include a combination of oral therapy or surgery. As far as oral treatments are concerned, the doctor may prescribe any of the following types of therapies, depending on the patient’s existing condition:
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